Trichoplein, Keratin Filament Binding (TCHP) Peptide
TCHP
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN939497
Aperçu rapide pour Trichoplein, Keratin Filament Binding (TCHP) Peptide (ABIN939497)
Antigène
TCHP
(Trichoplein, Keratin Filament Binding (TCHP))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of TCHP antibody,
Alternative Names: TCHP control peptide, TCHP antibody Blocking Peptide, Anti-TCHP Blocking Peptide, trichoplein, keratin filament binding Blocking Peptide, MGC10854 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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Sujet
- TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
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Poids moléculaire
- 61 kDa
Antigène
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